Alterations in plasma proteome during acute COVID-19 and recovery

Abstract Background The severe course of COVID-19 causes cardiovascular injuries, although the mechanisms involved are still not fully recognized, linked, and understood.Their characterization is of great importance with the establishment of the conception of post-acute sequelae of COVID-19, referred to as long COVID, where blood clotting and endot

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Harnessing adenovirus in cancer immunotherapy: evoking cellular immunity and targeting delivery in cell-specific manner

Abstract Recombinant adenovirus (rAd) regimens, including replication-competent oncolytic adenovirus (OAV) and replication-deficient adenovirus, have been identified as potential cancer therapeutics.OAV presents advantages such as selective replication, oncolytic efficacy, and tumor microenvironment (TME) remodeling.In this perspective, the princip

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